The development of biological devices to allow the noninvasive control of cell fate and function can potentially revolutionize the field of regenerative medicine.
Quantum entanglement is essential for precision in magnetoreception.
Magnetoreception is a sense which allows an organism to detect a magnetic field.
In 2000, cryptochrome was proposed as the "magnetic molecule". Magnetic fields trigger quantum chemical reactions in proteins called cryptochromes.
The second proposed model for magnetoreception relies on clusters composed of iron, a natural mineral with strong magnetism, otherwise known as Ferromagnetism. These iron clusters have been observed in magnetite.
Like the Marvel comic book hero, we are all iron men and women. Iron composes the heme of hemoglobin, the red pigment in our blood. It's stored in ferritin, a protein ubiquitous in almost all living organisms. And, most curiously, it's found in mineral form within the human brain.
That iron mineral is magnetite (Fe3O4), and its name is an obvious clue to its most intriguing property: magnetite is the most magnetic of Earth's naturally-occurring minerals.
Various studies have shown that brain cells respond to external magnetic fields. Receptor cells containing crystals of magnetite could register changes in magnetic fields and report this information to the brain.
Magnetite is indeed present in its crystalline form throughout the human brain, with particularly high concentrations in the cerebellum and brain stem. Moreover, it's highly likely that this magnetite is produced within our cells.
In fact, magnetic iron oxide nanoparticles, magnetite/maghemite, have been identified in human tissues, including the brain, meninges, heart, liver, and spleen.
Moreover, magnetite nanoparticles can be exploited for hyperthermia-based cancer therapy, where the heat-induced by application of an alternating magnetic field causes necrosis of cancer cells but does not damage the surrounding normal tissue.
Results indicate the possibility of an additional therapeutic mechanism of intense THz pulses, due to the potential for targeted suppression of pro-mitotic activity in diseased tissue.
The pineal gland and choroid plexus are also sensitive to static magnetic fields.
The ‘Third Eye’ Connection
New evidence points towards interactions between the brain and higher states of consciousness.
Several spiritual philosophies contain the notion of an inner ‘third eye’, related to the pineal gland, to which is attributed significance in mystical awakening or enlightenment, higher states of consciousness, and extrasensory perception (ESP).
The pineal gland, being the only singular structure in the brain and having a strategic position between the two halves, is believed to connect between intellect and the body. This ‘third eye’ could be activated to spiritual world frequencies, enabling a person to have the sense of all-knowing, godlike euphoria, and oneness all around him, says Dr. Panagariya.
Dr. Panagariya, presently a member of the Rajasthan State Planning Board, has in his study referred to another recent discovery of interest to psychic researchers proving that the human brain contains magnetite (ferrous oxide), which renders the brain sensitive to the Earth’s magnetic fields.
“It has long been known that birds and other animals use magnetite in their brains to aid in navigation. Magnetite is especially concentrated in the pineal gland and the temporal lobes,” says Dr. Panagariya, offering a scientific explanation to the spiritual, mystical, and paranormal experiences.
Melatonin, the main product secreted by the pineal gland during the dark phase of the photoperiod, is capable of influencing microfilament, microtubule, and IF organization by acting as a cytoskeletal modulator.
Actin microfilament organization also changes in the presence of melatonin stimulated by the pineal gland in the presence of terahertz frequency.
Also, actin has been implicated in the transcellular pathway of ion and water transport by microfilament interaction with transmembrane proteins involved in vectorial transport
In other words, actin has been shown to influence the pineal gland.
Actin Polymerization Modulation by Terahertz
Actin's primary role in the cell is to form microfilaments that serve various functions in the cell's structure, trafficking networks, migration, and replication.
Actin is one of the most conserved proteins throughout the evolution of eukaryotes. The force generated from ATP is actin-dependent. Actin and closely related proteins are present in all organisms, suggesting the common ancestor of all life on Earth had actin.
Actin participates in many important cellular processes, including muscle contraction, cell motility, cell division and cytokinesis, vesicle and organelle movement, cell signaling, and the establishment and maintenance of cell junctions and cell shape.
A cell's ability to dynamically form microfilaments provides the scaffolding that allows it to rapidly remodel itself in response to its environment or to the organism's internal signals, for example, to increase cell membrane absorption or increase cell adhesion in order to form cell tissue. Other enzymes or organelles such as cilia can be anchored to this scaffolding in order to control the deformation of the external cell membrane, which allows endocytosis and cytokinesis. It can also produce movement either by itself or with the help of molecular motors. Actin, therefore, contributes to processes such as the intracellular transport of vesicles and organelles as well as muscular contraction and cellular migration. It, therefore, plays an important role in embryogenesis, the healing of wounds, and the invasivity of cancer cells.
A large number of illnesses and diseases are caused by mutations in alleles of the genes that regulate the production of actin or of its associated proteins. The production of actin is also key to the process of infection by some pathogenic microorganisms. Mutations in the different genes that regulate actin production in humans can cause muscular diseases, variations in the size and function of the heart as well as deafness. The make-up of the cytoskeleton is also related to the pathogenicity of intracellular bacteria and viruses, particularly in the processes related to evading the actions of the immune system.
The actin in the cytoskeleton is involved in the pathogenic mechanisms of many infectious agents, including HIV.
Actin is important for maintaining the proper shape of the nucleus, chromatin reorganization, regulation of gene activity, gene expression modulation, cell movement, cell division, apoptosis, cellular adhesion and development, intracellular trafficking, mechanosensory function, intrinsic chirality, and immune response.
In addition to the physical force generated by actin polymerization, microfilaments facilitate the movement of various intracellular components by serving as the roadway along which a family of motor proteins called myosins travel.
Recent reports showed that THz frequency inhibits cell proliferation and changes the adhesive properties of the nerve cell membrane through actin.
Enhancement of actin polymerization by THz irradiation suggests a novel possibility of artificial manipulation of biomolecules and living cells using THz waves.
Because polymer formation of chemical and biological molecules is mostly sensitive to temperature, the simplest explanation for the enhancement of actin polymerization might be a transient increase of temperature due to the absorption of THz irradiation by water molecules.
It is known that irradiation with THz waves does not cause cellular or DNA damage. Therefore, THz irradiation should be a safe and novel technology for regulating the dynamics of actin polymerization and depolymerization in living cells. The actin dynamics in the cytoplasm play pivotal roles in the proliferation and motility of cells. In addition, actin dynamics in the cell nucleus are required for transcriptional regulation.
Indeed, some actin-binding chemical compounds are expected to act as anti-cancer drugs because actin dynamics contribute to the metastasis of cancer cells. As it is difficult to control the delivery and clearance of these chemicals in target cells, physical irradiation by THz waves could provide an advantage. Our findings suggest that THz waves could be applicable for artificial manipulation of these cellular functions through modulation of actin dynamics.
Results indicate that membrane injury or cell death is not induced by THz irradiation, but that manipulation of actin filaments in living cells might be induced by THz waves.
THz waves enable "soft" manipulation of macromolecules such as proteins, enabling changes to their higher-order structure without damaging.
THz irradiation affects not only the surface of the human body but also the tissue.
Actin is required for gene reprogramming, which is required for establishing iPS (induced pluripotent) stem cells.
Actin governs various functions of cells. Therefore, a variety of drugs have been developed for controlling actin filamentation, and applications of these drugs for medical purposes have been explored. However, these drugs are inefficient in their delivery into, and clearance from, cells. THz irradiation is a non-invasive method and could overcome these identified problems in drugs. THz wave is expected to become a novel tool for the manipulation of cellular functions through modifying actin filamentation.
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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